1. Provide professional DM input on Clinical Trial Team(s); Input to and review of all data relevant documents and process from DM perspective to ensure high quality and consistent data. 2. Ensure that data collected will be consistent with the grant protocol and planned analyses 3. Maintain clinical trial data accuracy through interim cross check of database for completeness and consistency. Identify errors and inconsistencies; resolve them to ensure high quality. 4. Management of CRO in Data management activities 5. Freeze and lock data as appropriate in time for statistical review, blinded interim quality review, interim and final database lock. 6. Ensures that such data is transmitted securely and is consistent with other data collected in the clinical trial. 7. Establish and maintain sound working relationships and effective communication within the BS&DM team and with other business area